OrphaNet reference

Coffin-Lowry syndrome 

May Cause

Anodontia or hypodontia

Body asymmetry

Bulbous nose

Congenital hypodontia

Coxa valga

Deafness

Defective dentition

Delayed bone age

Delayed closure of fontanelles

Delayed dentition

Dense epiphyses of hands and feet

Dense or thick skull

Dental defect

Drumstick distal phalanges

External ear malformation

Focally dense calvarium

Frontal bossing

Hydrops fetalis

Hypertelorism

Hypoplastic terminal phalanges

Irregular epiphysis

Joint laxity

Large fontanelle

Large hands for age

Limb asymmetry

Mitral valve disease

Pectus carinatum

Pectus excavatum

Premature tooth loss

Retarded skeletal maturation

Sclerotic epiphysis

Short and broad distal phalanges of hand

Thick skull

Thoracolumbar gibbus