Larsen syndrome

Larsen syndrome (LS) is a congenital disorder discovered in 1950 by Larsen and associates when they observed dislocation of the large joints and face anomalies in six of their patients. Patients with Larsen syndrome normally present with a variety of symptoms, including congenital anterior dislocation of the knees, dislocation of the hips and elbows, flattened facial appearance, prominent foreheads, and depressed nasal bridges. [Source: Wikipedia ]

Larsen syndrome dominant
Recessive Larsen syndrome
May Cause
Absent clavicle
Absent thumb
Accessory carpal or tarsal bones
Accessory epiphyses
Advanced bone age in a newborn
Arterial dilatation
Bowed bones
Bowed tubular bones
Broad distal phalanges
Broad thumb
Cervical kyphosis
Clavicle hypoplasia
Cleft lip/palate
Clubbing of digits
Congenital abnormality of great toe
Congenital elbow anomaly
Congenital foot deformity
Congenital joint subluxation
Congenital midface hypoplasia
Congenital short hands and feet
Congenital short limbs
Congenital vertebral abnormality
Contracted hand
Defective pubic ossification
Delayed bone age
Delayed ossification of the pubic bone
Depressed nasal bridge
Elbow dislocation
Facial hypoplasia
Fragmented, irregular, or sclerotic carpal or tarsal bones
Frontal bossing
Hip dislocation
Hip subluxation
Hypoplastic terminal phalanges
Hypoplastic thumb
Increased carpal angle
Joint laxity
Joint subluxation
Large thumb
Laryngeal anomaly
Metatarsus adductus
Multiple calcaneal ossification centers
Nail aplasia
Nail deformity
Nail dystrophy
Nail hypoplasia
Pubic bone nonossification
Retarded skeletal maturation
Ribbon-like ribs
Short and broad distal phalanges of hand
Short metacarpal
Short metatarsal
Short metatarsals
Short squat bones
Short thumb
Slender clavicle
Small orbit
Thin clavicle
Thin ribs
Type B pelvis
Vertebral coronal cleft
Vertebral malsegmentation
Wavy ribs
Wide thumb