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IUGR: etiology


UTEROPLACENTAL INSUFFICIENCY (80%)
  • maternal causes
    • deficient supply of nutrients: smoking, malnutrition, multiple gestations, anemia, high altitude
    • maternal vascular disease (more common): severe diabetes,
  • primary placental causes
    • extensive placental infarctions, chronic partial separation, placenta previa

PRIMARY FETAL CAUSES (20%)
  • decreased intrinsic growth; symmetrical IUGR
  • congenital heart disease, genitourinary anomalies, CNS anomalies, chromsomal abnormalities (trisomy 13, 18, 21), viral infection (rubella, CMV)

see also: intrauterine growth retardation (IUGR)


Yong H. Hahn, MD  -  2 February 1995
Last updated:  1 October 2013


 

Related CHORUS documents:
intrauterine growth retardation (IUGR)
IUGR: phenotypes
biophysical profile
fetal doppler study
multiple gestation
meconium aspiration syndrome

 

Copyright © 2013, Charles E. Kahn, Jr.