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vitamin D
(1) (2) (3)
7-DHC -----> D3 -----> 25-OH vit D3 -----> 1,25-OH vit D3
- (1) skin
- sunlight converts 7-dehydrocholesterol
to vit D3 (cholecalciferol)
- (2) liver
- 25-hydroxylation
- (3) kidneys
- 1-hydroxylation to active form
- requires parathyroid hormone (PTH)
- vit D promotes calcium absorption from bowel
- deficiency ==> rickets
Charles E. Kahn, Jr., MD - 2 February 1995
Last updated: 1 October 2013
Copyright © 2013, Charles E. Kahn, Jr.
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