brain iron

Normal
- Infant: NONE
- Adult: globus pallidum, substantia nigra, red nucleus, dentate nucleus
- Aging: (adult) + putamen
Degenerative disease
- Parkinson disease: putamen, SN compacta
- Huntington disease: caudate, putamen
- Alzheimer disease: cerebral cortex
- Hallervorden-Spatz disease
MS: thalamus, putamen
Others
- AVM: malformation + rim
- Bleed: rim macrophages
- Hemorrhagic CVA: gyral / basal ganglia

MRI: low T1 + T2 signal, blooming on gradient echo

Charles E. Kahn, Jr., MD - 9 March 1995
Last updated: 1 October 2013