CHORUS

Collaborative Hypertext of Radiology

Musculoskeletal system

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osteomalacia

etiology:

• dietary deficiency of vitamin D3, lack of solar irradiation
• deficiency of metabolism of vitamin D
  • chronic renal tubular disease
  • phenobarbitol, diphenylhydantoin
• decreased absorption of vitamin D (malabsorption, gastrectomy)
• diphosphonates (decrease calcium deposition; rx. for Paget's)

findings:

• osteopenia
• bone softening/deformity: hourglass thorax, bowing of long bones
• increased fractures, biconcave vertebral bodies
• mottled skull
• pseudofractures

Related CHORUS documents: necrotizing enterocolitis acute upper GI hemorrhage carcinoid tumor pseudo-fracture (Looser zone) rickets Schmorl node

Copyright © 2013, Charles E. Kahn, Jr.