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gastric carcinoma


  • 3rd most common GI malignancy (after colorectal + pancreas)
  • 95% adenocarcinoma (rarely squamous cell or adenoacanthoma)

  • predisposing factors:
    • pernicious anemia (2X risk)
    • chronic atrophic gastritis
    • adenomatous + villous polyp (7-27% are malignant)
    • gastrojejunostomy

types:
  1. polypoid / fungating
  2. ulcerating / penetrating (70%)
  3. infiltrating / scirrous = linitis plastica
  4. superficial spreading carcinoma
    • confined to mucosa/submucosa; 95% 5-year survival
    • patch of nodularity; little loss of elasticity

location:
  • 60% lesser curvature
  • 30% GE junction
  • 10% greater curvature

probability of malignancy of an ulcer:
  • fundus 90%
  • greater curvature 70%
  • lesser curvature 10-15%


Yong H. Hahn, MD  -  2 February 1995
Last updated:  1 October 2013


 

Related CHORUS documents:
gastric ulcers
colon carcinoma
liver metastases
gastric outlet obstruction
pancreatic adenocarcinoma
Carman meniscus sign

 

Copyright © 2013, Charles E. Kahn, Jr.