CHORUS
Collaborative Hypertext of Radiology
Multisystem entities
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mastocytosis
- proliferation of mast cells
- seen in hematopoietic regions of skeleton
- sclerotic bone lesions
- diffuse osteosclerosis
- discrete, irregular, sclerotic nodules
- rarely lytic lesions with densely sclerotic margins
- mast cells elaborate histamine
==> flushing, tachycardia, nausea, diarrhea
- pigmented, pruritic rash (urticaria pigmentosa)
- hepatosplenomegaly, adenopathy
- thrombocytopenia; increased or decreased WBCs
Charles E. Kahn, Jr., MD - 2 February 1995
Last updated: 1 October 2013
Copyright © 2013, Charles E. Kahn, Jr.
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