CHORUS
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Letterer-Siwe disease
Acute diseminated form of histiocytosis X
- age 0 - 1 yr
- worst prognosis (70% mortality)
- visceral involvement: hepatosplenomegaly
- purpura, anemia, lymphadenopathy
- bone: extensive lytic skull lesions, "raindrop" skull
Charles E. Kahn, Jr., MD - 2 February 1995
Last updated: 1 October 2013
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Copyright © 2013, Charles E. Kahn, Jr.