CHORUS
Collaborative Hypertext of Radiology
Multisystem entities
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immunodeficiency disorders
- B-cell (antibody) deficiency:
- high-grade pathogens: pneumococcus, strep, H. flu
- chronic sinopulmonary disease
- usual survival to adulthood
- T-cell (cellular) deficiency:
- low-grade pathogens: fungi, viruses, Pneumocystic
- growth retardation, diarrhea, delayed anergy
- short life-span
- susceptible to graft vs. host (GvH) disease
- e.g.: DiGeorge syndrome, Nezelhof syndrome
Note: increased risk of malignancy
Charles E. Kahn, Jr., MD - 2 February 1995
Last updated: 1 October 2013
Copyright © 2013, Charles E. Kahn, Jr.
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