CHORUS
Collaborative Hypertext of Radiology
Multisystem entities
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amyloidosis
rare, usually systemic disease
- extracellular deposition of insoluble
B-pleated sheet configured protein that stains with Congo red
- systemic (80-90%)
- primary
- M > F
- 55-60y
- often presents with renal insufficiency or CHF
- secondary
- localized (10-20%)
manifestations
- chest
- tracheal nodules/narrowing
- pulmonary nodules
- diffuse parenchymal pattern
- heart: enlargement (Tc-99m pyrophosphate positive)
- kidneys
- large kidneys
- small kidneys
- focal masses
- calcifications
- bladder/ureters: focal or diffuse infiltration
- bones: pain/weakness associated with lytic lesions +/- calcium
- joints (shoulder, elbow, wrist, hip)
- ST enlargement
- subchondral cysts
- gastrointestinal tract
Brian Funaki, MD - 14 February 1995
Last updated: 1 October 2013
Copyright © 2013, Charles E. Kahn, Jr.
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