CHORUS
Collaborative Hypertext of Radiology
Musculoskeletal system
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Paget disease
disease of unknown etiology involving destruction and reparation
- age > 40y; M:F 2:1
- skull
- osteoporosis circumscripta (outer table destroyed only)
- "cotton wool" appearance
- increased hat size!
- spine
- monostotic vertebral involvment usually
- pelvis
- affected in 2/3 cases
- consists of cortical thickening
- enlargement of pubis/ischium
- coarse trabecular pattern
- extremities
- "blade of grass" appearance
- elevation of alk phos (up to 20X), normal calcium, normal phosphorus
- complications:
- path fractures in 8% cases (usu. femur = "shepard's crook")
- malignant degeneration (usu. osteosarcoma-50%, fibrosarcoma-25%)
Brian Funaki, MD - 6 February 1995
Last updated: 1 October 2013
Copyright © 2013, Charles E. Kahn, Jr.
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