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Multisystem entities

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diabetes insipidus

hypothalamic
  • vasopressin production is reduced to < 10%
    • rare genetic disorder
    • pituitary destruction: craniopharyngioma, surgery, trauma, meningitis, histiocytosis X

  • psychogenic (water intoxication)
    • compulsive intake of large amounts of fluid
    • inhibition of normal vasopressin production

  • primary nephrogenic
    • rare sex-linked recessive disorder (infants and young males)
    • tubules and collecting system unresponsive to vasopressin

  • secondary nephrogenic
    • drug toxicity, analgesic nephropathy, sickle cell, hypokalemia, hypercalcemia, chronic uremic nephropathy, postobstructive nephropathy, amyloidosis, sarcoidosis

    Yong H. Hahn, MD  -  2 February 1995
    Last updated:  1 October 2013


     

    Related CHORUS documents:
    eosinophilic granuloma
    Hand-Schueller-Christian disease
    histiocytosis X
    Letterer-Siwe disease
    Coccidioides
    pancreatic islet-cell tumors

     

    Copyright © 2013, Charles E. Kahn, Jr.