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Musculoskeletal system

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acromegaly


excess growth hormone due to eosinophilic adenoma/hyperplasia

  • osseous enlargement (phalangeal tufts, vertebrae)
  • flared ends of long bones
  • cystic changes in carpals, femoral trochanters
  • osteoporosis

  • spade-like hand
  • prognathism (elongation of mandible) in few cases
  • sellar enlargement and erosion
  • enlarged paranasal sinuses (esp. frontal): 75%
  • calvarial hyperostosis (esp. inner table)
  • enlarged occipital protuberance
  • vertebrae: posterior scalloping (30%), anterior new bone, loss of disc space

  • heel pad > 25 mm
  • premature osteoarthritis (commonly knees)


Yong H. Hahn, MD  -  2 February 1995
Last updated:  1 October 2013


 

Related CHORUS documents:
posterior vertebral scalloping
somatotrophic adenoma
heel pad
increased skull thickness
pituitary adenoma
Marfan syndrome

 

Copyright © 2013, Charles E. Kahn, Jr.