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malignant melanoma: staging

Clark staging:
  • level I: all tumor cells above basement membrane (in situ)
  • level II: tumor extends to papillary dermis
  • level III: tumor extends to interface between papillary and reticular dermis
  • level IV: tumor extends between bundles of collagen of reticular dermis
  • level V: tumor invasion of sucutaneous tissue (87% metastases)

Breslow staging:

  • thin: < 0.75 mm depth of invasion
  • intermediate: 0.76 - 3.99 mm depth of invasion
  • thick: > 4 mm depth of invasion

see: malignant melanoma

Yong H. Hahn, MD  -  2 February 1995
Last updated:  1 October 2013


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Copyright © 2013, Charles E. Kahn, Jr.