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malignant melanoma: staging
Clark staging:
- level I: all tumor cells above basement membrane (in situ)
- level II: tumor extends to papillary dermis
- level III: tumor extends to interface between papillary and reticular dermis
- level IV: tumor extends between bundles of collagen of reticular dermis
- level V: tumor invasion of sucutaneous tissue (87% metastases)
Breslow staging:
- thin: < 0.75 mm depth of invasion
- intermediate: 0.76 - 3.99 mm depth of invasion
- thick: > 4 mm depth of invasion
see: malignant melanoma
Yong H. Hahn, MD - 2 February 1995
Last updated: 1 October 2013
Copyright © 2013, Charles E. Kahn, Jr.