CHORUS - home page


Collaborative Hypertext of Radiology

Technical stuff / Miscellany



inflammation: gallium imaging

  • leakage of protein-bound Ga-67 into extracellular space secondary to increased capillary permeability
  • Ga-67 is preferentially bound to nonviable PMNs and macrophages
  • leukocyte incorporation (rich in lactoferrin)
  • bacterial uptake (siderophores)
  • inflammtory tissue stimulates lactoferrin production
for chronic abdominal inflammation:
  • 67% sensitivity; 64% specificity; 13% false negatives; 5% false positive
  • dose: 5 mCi; imaging: 24, 48, 72 hours
  • diffuse uptake in peritonitis
  • localized uptake in acute pyogenic abscess, phlegmon, acute cholecystitis, acute pancreatitis, acute gastritis, diverticulitis, inflammatory bowel disease, surgical wound, pyelonephritis, perinephric abscess

see: gallium indications, gallium vs. indium

Yong H. Hahn, MD  -  7 July 1995
Last updated:  1 October 2013


Related CHORUS documents:
gallium: indications
gallium-67 citrate
gallium vs. indium
craniosynostosis (premature sutural fusion)
Hodgkin disease: gallium imaging
systemic lupus erythematosus (SLE)


Copyright © 2013, Charles E. Kahn, Jr.