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Multisystem entities

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Reye syndrome

hepatitis + encephalitis following viral upper respiratory tract infection with H/O large dose of aspirin

  • age: children and young adults
  • obtundation rapidly followed by coma
  • 15 - 85% mortality (from white matter edema and demyelination)

CT findings:
  • initially (within 2-3 days) small ventricles
  • later progressive enlargement of lateral ventricles and sulci
  • markedly diminished attenuation of white matter

diagnosis by liver biopsy: fatty infiltration

Yong H. Hahn, MD  -  2 February 1995
Last updated:  1 October 2013


 

Related CHORUS documents:
fatty liver
Cushing disease
Crohn disease: extraintestinal manifestations
Cushing syndrome
hepatomegaly
Crohn disease

 

Copyright © 2013, Charles E. Kahn, Jr.