CHORUS
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oxalosis
rare inborn error of metabolism (autosomal recessive)
- excessive amounts of oxalic acid combine with calcium and deposit throughout the body (kidney, soft tissue, bone)
- early death in childhood
- hyperoxaluria (> 50 mg/day in urine)
- progressive renal failure
- osteoporosis
- erosions on concave side of metaphysis near epiphysis
- bone-within-bone appearance of spine
- medullary nephrocalcinosis
- secondary to disturbance of bile acid metabolism: i.e., s/p jejunal bypass, ileal resection, blind loop syndrome, Crohn's, increased ingestion of green leafy vegetables, pyridoxine deficiency, etc.
Yong H. Hahn, MD - 2 February 1995
Last updated: 1 October 2013
Copyright © 2013, Charles E. Kahn, Jr.