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Multisystem entities

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Werner syndrome


"cataract in connection with scleroderma"
  • rare; unknown etiology
  • M = F

  • premature aging, short stature
  • thin, atrophic extremities
  • generalized osteoporosis
  • accelerated atherosclerosis (calcification of arteries, heart valves)
  • beaked nose

  • multiple infections (incl. osteomyelitis)
  • scleroderma-like skin changes
  • increased incidence of malignancy: GI tract, lung, kidney, ovary, breast


Charles E. Kahn, Jr., MD  -  2 February 1995
Last updated:  1 October 2013


 

Related CHORUS documents:
progeria (Hutchinson-Gilford) syndrome
achondroplasia
adrenoleukodystrophy
histoplasmosis
giant cell astrocytoma
portal hypertension

 

Copyright © 2013, Charles E. Kahn, Jr.